File(s) not publicly available

Use of the myocardial performance index in decreased fetal movement assessment: A case-control study

journal contribution
posted on 14.04.2021, 04:25 by Daphne Ho, Jingjing Wang, Yvette Homann, Jennifer AlphonseJennifer Alphonse, Geraldine Beirne, Alec W Welsh, Amanda Henry
Objectives: To determine whether there are any fetal cardiac function changes, as measured by the myocardial performance index (MPI), in pregnancies complicated by decreased fetal movement (DFM). Methods: We performed a prospective cross-sectional case-control study of 50 DFM and 50 uncomplicated third-trimester pregnancies matched within 2 gestational weeks. Routine ultrasound growth and well-being parameters as well as MPI were measured. Average MPI measurements and its component values were compared between the DFM and the control group, as were demographics, other ultrasound data, and perinatal outcomes. Results: Average left MPI (LMPI) and right MPI (RMPI) was similar between groups (LMPI: 0.54 ± 0.08 [DFM], 0.53 ± 0.08 [controls], p = 0.76; RMPI: 0.60 ± 0.12 (DFM), 0.59 ± 0.11 [controls], p = 0.79). However, subgroup analysis of DFM fetuses with (n = 20) or without (n = 30) any adverse perinatal outcome demonstrated modestly higher average RMPI and LMPI in the adverse perinatal outcome group (RMPI: 0.64 ± 0.08 vs. 0.57 ± 0.13, p = 0.02; LMPI: 0.56 ± 0.07 vs. 0.52 ± 0.07, p = 0.052). Conclusion: The MPI did not demonstrate clinically usable differences between the overall DFM population and controls. However, higher LMPI and RMPI values in the exploratory subgroup of DFM fetuses with adverse perinatal outcomes may warrant further exploration of the MPI in DFM. © 2017 S. Karger AG, Basel.

History

Volume

43

Issue

3

Start Page

1

End Page

10

Number of Pages

10

eISSN

1421-9964

ISSN

1015-3837

Location

Switzerland

Publisher

S. Karger

Language

eng

Peer Reviewed

Yes

Open Access

No

Acceptance Date

21/04/2017

External Author Affiliations

University of New South Wales

Era Eligible

Yes

Medium

Print-Electronic

Journal

Fetal Diagnosis and Therapy