Smart farming has the potential to overcome the challenge of 2050 to feed 10 billion people. Both artificial intelligence (AI) and the internet of things (IoT) have become critical prerequisites to smart farming due to their high interoperability, sensors, and cutting-edge technologies. Extending the role of responsible leadership, this paper proposes an AI and IoT based smart farming system in Bangladesh. With a comprehensive literature review, this paper counsels the need to go beyond the simple application of traditional farming and irrigation practices and recommends implementing smart farming enabling responsible leadership to uphold sustainable agriculture. It contributes to the current literature of smart farming in several ways. First, this paper helps to understand the prospect and challenges of both AI and IoT and the requirement of smart farming in a nonwestern context. Second, it clarifies the interventions of responsible leadership into Bangladesh’s agriculture sector and justifies the demand for sustainable smart farming. Third, this paper is a step forward to explore future empirical studies for the effective and efficient use of AI and IoT to adopt smart farming. Finally, this paper will help policymakers to take responsible initiatives to plan and apply smart farming in a developing economy like Bangladesh.