Restricting tylosin use to the final 34 days on feed is not effective for controlling liver abscesses in steers

This study was conducted to determine if tylosin phosphate use could be restricted to the final 34 d on feed as a strategy to decrease antibiotic use, while still decreasing the incidence of liver abscesses. Crossbred steers (n = 336; 453 ± 15.5 kg initial BW) were blocked by previous treatment and randomly assigned, within block, to one of three treatments, which included a negative control (no tylosin), tylosin fed continuously for the 115-day study, or fed only the final 34 d on feed.