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Reliability of orthostatic responses in healthy men aged between 65 and 75 years

journal contribution
posted on 06.12.2017, 00:00 by T Gabbett, Gregory GassGregory Gass
The purpose of this study was to investigate the short-, medium- and long-term reproducibility of cardiovascular responses during 90 degree head-up tilt (HUT) in healthy older men. Twenty-eight healthy male subjects aged 69 (95% confidence intervals, 68-70) years participated in the study. Eight subjects underwent duplicate 90 degree HUT tests on consecutive days, while 20 subjects underwent four 90 degree HUT tests performed at baseline, and after 1 week, 1 month and 1 year. Following a 20-min supine resting period, each subject was rapidly tilted to the upright vertical position (90 degree HUT) and remained in that position for 15 min. Beat-by-beat recordings of mean (MAP), systolic (SBP) and diastolic (DBP) pressures were made via Finapres, while heart rate (HR) was monitored continuously from an electrocardiogram. No significant test-retest differences (P > 0.05) were observed for the changes in HR, MAP, SBP or DBP during 90 degree HUT. These measurements demonstrated high reproducibility (intraclass correlation coefficient, r = 0.91-0.99, P < 0.05). The supine resting and tilted HR, MAP, SBP and DBP over the 1-week, 1-month and 1-year period were not significantly different (P > 0.05) from baseline, and demonstrated high reproducibility (intraclass correlation coefficient, r = 0.82-0.98, P < 0.05).The results of this study demonstrate that in healthy older men, cardiovascular responses during orthostasis are highly reproducible, and this reproducibility is maintained over a 12-month period. These findings demonstrate that the 90 degree HUT test offers a reproducible method of monitoring longitudinal orthostatic responses in healthy older men.

Funding

Category 1 - Australian Competitive Grants (this includes ARC, NHMRC)

History

Volume

90

Issue

4

Start Page

587

End Page

592

Number of Pages

6

eISSN

1469-445X

ISSN

0958-0670

Location

United Kingdom

Publisher

Wiley-Blackwell

Language

en-aus

Peer Reviewed

Yes

Open Access

No

External Author Affiliations

Griffith University; Queensland Academy of Sport; TBA Research Institute;

Era Eligible

No

Journal

Experimental physiology.