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Polyunsaturated fatty acids modify colorectal epithelial cell cytokine expression in a leucocyte co-culture model in response to probiotic bacteria

journal contribution
posted on 12.02.2020, 00:00 by KL Bentley-Hewitt, CE De Guzman, J Sutherland, T Mandimika, A Narbad, EK Lund
Diets high in n–3 polyunsaturated fatty acids (PUFAs) have been linked to improved colorectal health(1). One possible mechanism underlying this observation is that different PUFAs affect the immune response of epithelial cells to beneficial bacteria such as probiotics. The aim of this study was therefore to test whether pre-incubation of cells with different PUFAs would modify the epithelial cell response to probiotic bacteria.

Funding

Category 2 - Other Public Sector Grants Category

History

Volume

69

Issue

OCE4

Start Page

328

End Page

328

Number of Pages

1

eISSN

1475-2719

ISSN

0029-6651

Publisher

Cambridge University Press (CUP)

Language

en

Peer Reviewed

Yes

Open Access

No

External Author Affiliations

Institute of Food Research, UK; New Zealand Plant and Food Research

Era Eligible

No

Journal

Proceedings of the Nutrition Society