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Phytochemicals produced to combat plant pathogens as a source of novel antimicrobial compounds against multidrug-resistant bacteria

journal contribution
posted on 10.03.2020, 00:00 by A Aunjum, Andrew Taylor-RobinsonAndrew Taylor-Robinson
The increasing trend of bacterial resistance to existing classes of major antibiotics for prescribed use has placed considerable emphasis on the development of new efficient antibacterial regimens. Throughout recorded history medications derived from herbal extracts have been harnessed to alleviate the clinical symptoms of all types of illness. Phytochemicals form the basis of a vast array of present day or past medicines and hence exotic plants continue to attract attention for novel drug development. Most compounds that are exploited for therapeutic purposes are synthesized by plants as a constitutive part of their innate defence mechanisms. Substances from infected plants are afforded less attention for potential antimicrobial properties because their production is limited to the period of infestation of a given pathogen. This article aims to shed light on our knowledge of induced defence compounds and to compare this to information available on constitutively expressed compounds extracted from plants. Although induced resistance of plants has attained a growing research momentum, further investigation is merited into, for instance, the continuous and specific interactions between plants and herbivores. Such research will help to address the importance of plant toxins elicited by inducible defence mechanisms to meet the great public health challenge of multidrug-resistant bacteria.

History

Volume

15

Start Page

55

End Page

60

Number of Pages

6

ISSN

0972-4796

Publisher

Research Trends, India

Peer Reviewed

Yes

Open Access

No

External Author Affiliations

Biotechnology & Genetic Engineering Discipline, Khulna University, Bangladesh

Era Eligible

Yes

Journal

Current Topics in Phytochemistry