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Multilevel modelling of the risk of malaria among children aged under five years in Nigeria

journal contribution
posted on 27.07.2021, 00:38 by Victor M Oguoma, Anayochukwu E Anyasodor, Adeniyi AdeleyeAdeniyi Adeleye, Obiora A Eneanya, Evaristus C Mbanefo
Background: Malaria is still amajor cause ofmorbidity andmortality among children aged <5 y (U5s). This study assessed individual, household and community risk factors for malaria in Nigerian U5s. Methods: Data from the Nigerian Malaria Health Indicator Survey 2015 were pooled for analyses. This comprised a national survey of 329 clusters. Children aged 6–59 mo who were tested for malaria using microscopy were retained. Multilevel logit model accounting for sampling design was used to assess individual, household and community factors associated with malaria parasitaemia. Results: A total of 5742 childrenwere assessed for malaria parasitaemia with an overall prevalence of 27% (95% CI 26 to 28%). Plasmodium falciparum constituted 98% of the Plasmodium species. There was no significant difference in parasitaemia between older children and those aged ≤12 mo. In adjusted analyses, rural living, northwest region, a household size of >7, dependence on river and rainwater as primary water source were associated with higher odds of parasitaemia, while higher wealth index, all U5s who slept under a bed net and dependence on packaged water were associated with lower odds of parasitaemia. Conclusion: Despite sustained investment in malaria control and prevention, a quarter of the overall study population of U5s have malaria. Across the six geopolitical zones, the highest burden was in children living in the poorest rural households.

History

Volume

115

Issue

5

Start Page

482

End Page

494

Number of Pages

13

eISSN

1878-3503

ISSN

0035-9203

Location

England

Publisher

Oxford University Press (OUP)

Language

eng

Peer Reviewed

Yes

Open Access

No

Acceptance Date

26/08/2020

External Author Affiliations

Charles Darwin University; Charles Sturt University; Biomedical Research Institute, Biomedical Research Institute, USa

Era Eligible

Yes

Medium

Print

Journal

Transactions of the Royal Society of Tropical Medicine and Hygiene