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Modulation of corticomotor excitability after maximal or sustainable-rate repetitive finger movement is impaired in Parkinson’s disease and is reversed by levodopa

journal contribution
posted on 06.12.2017, 00:00 by Wei-Peng TeoWei-Peng Teo, J Rodrigues, F Mastaglia, G Thickbroom
Objectives: In healthy subjects, fatiguing exercises induce a period of post-exercise corticomotor depression (PECD) that is absent in Parkinson’s disease (PD). Our objective is to determine the time-course of corticomotor excitability changes following a 10-s repetitive index finger flexion–extension task performed at maximal voluntary rate (MVR) and a slower sustainable rate (MSR) in PD patients OFF and ON levodopa.

Funding

Category 1 - Australian Competitive Grants (this includes ARC, NHMRC)

History

Volume

125

Issue

3

Start Page

562

End Page

568

Number of Pages

7

eISSN

1872-8952

ISSN

1388-2457

Location

Ireland

Publisher

Elsevier

Language

en-aus

Peer Reviewed

Yes

Open Access

No

External Author Affiliations

University of Western Australia;

Era Eligible

Yes

Journal

Clinical neurophysiology.