Melatonin use in managing insomnia in children with autism and other neurogenetic disorders - An assessment by the international pediatric sleep association (IPSA)
journal contribution
posted on 2025-04-09, 00:29authored byS Kotagal, B Malow, K Spruyt, G Wang, CE Bolaños Almeida, LM Tavera Saldaña, Sarah BlundenSarah Blunden, I Narang, OS Ipsiroglu, O Bruni, BG Strazisar, N Simakajornboon, ML Nunes, S Cortese
Though it is widely prescribed for improving sleep of children with autism and other neurogenetic disorders, there is a need for practical guidance to clinicians on the use of melatonin for managing insomnia in this population. Because data were either lacking or inconclusive, a task force was established by the International Pediatric Sleep Association (IPSA) to examine the literature based on clinical trials from 2012 onwards. A summary of evidence pertaining to melatonin's utility and potential side effects, practice-related caveats, and insights for use are published herewith.