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Ionone derivatives from Alternanthera sessilis

journal contribution
posted on 06.12.2017, 00:00 by C Ragasa, N Tremor, John Rideout
The chloroform extract of the air-dried leaves of Alternanthera sessilis afforded a mixture of diastereomers of a new ionone derivative 1 whose structures were elucidated by extensive 1D and 2D NMR spectroscopy and mass spectrometry. Oxidative clevage of 1 to aldehyde 3 with manganese dioxide confirmed diastereoisomerism arose from a racemic slide chain chiral centre. Antimicrobial tests on the mixture of diastereomers and the derivative indicated that they have low activities against Pseudomonas aeruginosa and Trichophyton mentagrophytes.

Funding

Category 1 - Australian Competitive Grants (this includes ARC, NHMRC)

History

Volume

4

Issue

2

Start Page

109

End Page

115

Number of Pages

7

eISSN

1028-6020

ISSN

1477-2213

Location

Abingdon, England

Publisher

Taylor & Francis

Language

en-aus

Peer Reviewed

Yes

Open Access

No

Era Eligible

No

Journal

Journal of Asian natural products research.