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Influence of intracellular toxin concentrations on cylindrospermopsin bioaccumulation in a freshwater gastropod (Melanoides tuberculata)

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posted on 06.12.2017, 00:00 authored by Susan KinnearSusan Kinnear, Leo Duivenvoorden, Larelle FabbroLarelle Fabbro, G Eaglesham
Scant information is available regarding the bioaccumulation of cylindrospermopsin (CYN) in aquatic organisms, particularly in invertebrates. This study examined toxin bioconcentration and bioaccumulation in the aquatic snail, Melanoides tuberculata, following exposure to freeze-thawed whole cell extracts and a live Cylindrospermopsis raciborskii culture containing CYN. Both bioconcentration and bioaccumulation were evident, but exposure to toxin in the freeze-thawed solutions resulted in minor tissue contamination in comparison that resulting from live C. raciborskii exposure. Thus, whilst CYN uptake resulted from both extracellular and intracellular exposures, the availability of intracellular toxin was critical in affecting tissue CYN values. M. tuberculata did not bioconcentrate CYN into the shell. Bioaccumulation of the analog deoxy-CYN was also recorded. Knowledge of intracellular toxin concentrations may be critical in evaluating the bioaccumulation, ecological and human health risks associated with contaminated systems. Keywords: Cylindrospermopsis raciborskii, bioaccumulation, bioconcentration, blue-green algae, cyanobacteria, deoxy-cylindrospermopsin.

Funding

Category 1 - Australian Competitive Grants (this includes ARC, NHMRC)

History

Volume

47

Issue

5

Start Page

497

End Page

509

Number of Pages

13

ISSN

0041-0101

Location

Oxford

Publisher

Elsevier

Language

en-aus

Peer Reviewed

Yes

Open Access

No

External Author Affiliations

Centre for Environmental Management; Centre for Plant and Water Science; Scientific Services; TBA Research Institute;

Era Eligible

Yes

Journal

Toxicon.