Green tea catechins and blood pressure: A systematic review and meta-analysis of randomised controlled trials
journal contribution
posted on 2018-08-01, 00:00authored byS Khalesi Taharoom, J Sun, N Buys, A Jamshidi, E Nikbakht-Nasrabadi, H Khosravi-Boroujeni
Purpose Although previous literature has reported that
regular green tea consumption may improve blood pressure,
the evidence from these studies is not consistent. The
present study systematically reviewed randomised controlled
trials and examined the effect of green tea consumption
on blood pressure using meta-analysis.
Methods Search of ProQuest, PubMed, Scopus and
Cochrane Library (CENTERAL) was conducted, to identify
eligible articles. Articles from 1995 to 2013 were the effect of combined trials.
Result Thirteen studies were included in the meta-analysis.
Green tea consumption significantly changed systolic
blood pressure, by -2.08 mm Hg (95 % CI -3.06, -1.05),
and diastolic blood pressure, by -1.71 mm Hg (95 % CI
-2.86, -0.56), compared to the control. Changes in lipid
profile, blood glucose and body mass index were also
assessed in the meta-analysis. A significant reduction was
found in total cholesterol (-0.15 mmol/L [95 % CI -0.27,
-0.02]) and low-density lipoprotein cholesterol
(-0.16 mmol/L [95 % CI -0.22, -0.09]). Changes in
other parameters did not reach statistical significance.
Subgroup analysis suggested a greater reduction in both
systolic and diastolic blood pressure in studies that included
participants with a baseline mean systolic blood pressure
of C130 mm Hg, and studies involving consuming
green tea as an extract.
Conclusion The present meta-analysis suggests that green
tea and its catechins may improve blood pressure, and the
effect may be greater in those with systolic blood pressure
C130 mm Hg. The meta-analysis also suggests that green
tea catechins may improve total and low-density lipoprotein
cholesterol.