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Functional design of electrolytic biosensor

journal contribution
posted on 19.07.2018, 00:00 by DM Gamage Preethichandra, EMI Mala Ekanayake, M Onoda
A novel amperometric biosensbased on conjugated polypyrrole (PPy) deposited on a Pt modified ITO (indium tin oxide) conductive glass substrate and their performances are described. We have presented a method of developing a highly sensitive and low-cost nano-biosensor for blood glucose measurements. The fabrication method proposed decreases the cost of production significantly as the amount of noble metals used is minimized. A nano-corrugated PPy substrate was developed through pulsed electrochemical deposition. The sensitivity achieved was 325 mA/(Mcm2) and the linear range of the developed sensor was 50-60 mmol/l. Then the application of the electrophoresis helps the glucose oxidase (GOx) on the PPy substrate. The main reason behind this high enzyme loading is the high electric field applied across the sensor surface (working electrode) and the counter electrode where that pushes the nano-scale enzyme particles floating in the phosphate buffer solution towards the substrate. The novel technique used has provided an extremely high sensitivities and very high linear ranges for enzyme (GOx) and therefore can be concluded that this is a very good technique to load enzyme onto the conducting polymer substrates. © Published under licence by IOP Publishing Ltd.

History

Volume

924

Issue

Conference 1

Start Page

1

End Page

12

Number of Pages

12

eISSN

1742-6596

ISSN

1742-6588

Publisher

Institute of Physics Publishing , UK

Additional Rights

CC BY 3.0

Peer Reviewed

Yes

Open Access

Yes

External Author Affiliations

University of Hyogo, Japan

Era Eligible

Yes

Journal

Journal of Physics: Conference Series

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