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Dietary combination of potato resistant starch and red meat up-regulates genes involved in colonic barrier function of rats

journal contribution
posted on 31.01.2020, 00:00 by G Paturi, KL Bentley-Hewitt, CA Butts, Tafadzwa Nyanhanda, JA Monro, J Ansell
In a recent study, we have shown the favourable colonic effects of potato fibre and potato resistant starch through increased proliferation of bifidobacteria, lactobacilli or elevated short‐chain fatty acids (SCFAs) levels in rats fed a red meat‐based diet (Paturi et al., 2012c). Our hypothesis was that these changes in the microbiota and their metabolism may have positively influenced gene expression in the colon, given that beneficial bacteria such as bifidobacteria and lactobacilli are capable of enhancing the intestinal epithelial cell functions. Therefore, in the present study, we set out to investigate how the consumption of fermentable fibres, alongside a red meat diet affected the expression of genes involved in various protective mechanisms in the colon of rats.

Funding

Category 3 - Industry and Other Research Income

History

Volume

48

Issue

11

Start Page

2441

End Page

2446

Number of Pages

6

eISSN

1365-2621

ISSN

0950-5423

Publisher

Wiley-Blackwell Publishing, USA

Peer Reviewed

Yes

Open Access

No

Acceptance Date

11/05/2013

External Author Affiliations

The New Zealand Institute for Plant and Food Research Limited

Era Eligible

Yes

Journal

International Journal of Food Science and Technology