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Dengue epidemiology and pathogenesis: Images of the future viewed through a mirror of the past
journal contributionposted on 06.12.2017, 00:00 by R Islam, M Salahuddin, MS Ayubi, T Hossain, A Majumder, Andrew Taylor-Robinson, A Mahmud-Al-Rafat
Every year, millions of individuals throughout the world are seriously affected by dengue virus. The unavailability of a vaccine and of anti-viral drugs has made this mosquito-borne disease a serious health concern. Not only does dengue cause fatalities but it also has a profoundly negative economic impact. In recent decades, extensive research has been performed on epidemiology, vector biology, life cycle, pathogenesis, vaccine development and prevention. Although dengue research is still not at a stage to suggest definite hopes of a cure, encouraging significant advances have provided remarkable progress in the fight against infection. Recent developments indicate that both anti-viral drug and vaccine research should be pursued, in parallel with vector control programs.