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Can sesame consumption improve blood pressure? A systematic review and meta-analysis of controlled trials

journal contribution
posted on 02.05.2018, 00:00 authored by H Khosravi-Boroujeni, E Nikbakht, E Natanelov, Saman KhalesiSaman Khalesi
© 2017 Society of Chemical Industry Hypertension is a major risk factor for cardiovascular disease, myocardial infarction, stroke and renal failure. Sesame consumption may benefit blood pressure (BP) owing to its high polyunsaturated fatty acid, fibre, phytosterol and lignan contents. To clarify this, a systematic review and meta-analysis of controlled trials was conducted. The PubMed (MEDLINE), Cumulative Index to Nursing and Allied Health Literature (CINAHL) and Cochrane Library (Central) databases were systematically searched until August 2016. Eight controlled trials with a total of 843 participants met the eligibility criteria. A random effect meta-analysis showed that sesame consumption can reduce systolic BP (−7.83 mmHg, 95% CI: −14.12, −1.54; P < 0.05, I 2 = 99%) and diastolic BP (−5.83 mmHg, 95% CI: −9.58, −2.08; P < 0.01, I 2 = 98%). To reduce the heterogeneity, the meta-analysis was limited to high methodology quality trials (n = 4), which resulted in a significant reduction in systolic BP (−3.23 mmHg, 95% CI: −5.67, −0.79; I 2 = 33%) and a non-significant reduction in diastolic BP (−2.08 mmHg, 95% CI: −4.85, 0.69; I 2 = 62%). This study concluded that sesame consumption can reduce systolic and diastolic BP. However, further investigations with larger sample sizes and better methodology quality are required to confirm the BP-lowering effect of sesame consumption. © 2017 Society of Chemical Industry.

History

Volume

97

Issue

10

Start Page

3087

End Page

3094

Number of Pages

8

eISSN

1097-0010

ISSN

0022-5142

Publisher

Wiley

Peer Reviewed

Yes

Open Access

No

Acceptance Date

20/03/2017

External Author Affiliations

Griffith University;

Era Eligible

Yes

Journal

Journal of the Science of Food and Agriculture