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An automated framework for large scale retrospective analysis of ultrasound images

journal contribution
posted on 12.03.2020, 00:00 by P Sridar, A Kumar, Ann QuintonAnn Quinton, Narelle KennedyNarelle Kennedy, R Nanan, J Kim
Objective: Large scale retrospective analysis of fetal ultrasound (US) data is important in the understanding of the cumulative impact of antenatal factors on offspring's health outcomes. Although the benefits are evident, there is a paucity of research into such large scale studies as it requires tedious and expensive effort in manual processing of large scale data repositories. This study presents an automated framework to facilitate retrospective analysis of large scale US data repositories. Method: Our framework consists of four modules: (1) an image classifier to distinguish the Brightness (B)-mode images; (2) a fetal image structure identifier to select US images containing user-defined fetal structures of interest (fSOI); (3) a biometry measurement algorithm to measure the fSOIs in the images and, (4) a visual evaluation module to allow clinicians to validate the outcomes. Results: We demonstrated our framework using thalamus as the fSOI from a hospital repository of more than 80,000 patients, consisting of 3,816,967 antenatal US files (DICOM objects). Our framework classified 1,869,105 B-mode images and from which 38,786 thalamus images were identified. We selected a random subset of 1290 US files with 558 B-mode (containing 19 thalamus images and the rest being other US data) and evaluated our framework performance. With the evaluation set, B-mode image classification resulted in accuracy, precision, and recall (APR) of 98.67%, 99.75% and 98.57% respectively. For fSOI identification, APR was 93.12%, 97.76% and 80.78% respectively. Conclusion: We introduced a completely automated approach designed to analyze a large scale data repository to enable retrospective clinical research. © 2013 IEEE.

Funding

Other

History

Volume

7

Start Page

1

End Page

1

Number of Pages

1

eISSN

2168-2372

Publisher

Institute of Electrical and Electronics Engineers (IEEE)

Additional Rights

CC BY 4.0

Peer Reviewed

Yes

Open Access

Yes

Acceptance Date

29/10/2019

External Author Affiliations

The University of Sydney

Era Eligible

Yes

Journal

IEEE Journal of Translational Engineering in Health and Medicine