The paper reports on a fast EM algorithm for genomic selection by mapping QTL in genome-wide dense SNP marker data. The algorithm called emBayesB was used to analyse a 6000 SNP dataset simulated for the QTLMAS XII workshop. True breeding value was accurately predicted by GEBV with a correlation of 0.85 in the validation data, while the regression coefficient of 0.97 indicated unbiased predictions of breeding value. The results were similar to Bayesian MCMC estimates but were calculated in a fraction of the time. emBayesB was also able to accurately map the location of individual QTL which explain more than 1% of the total genetic variation.
History
Parent Title
Proceedings of the eighteenth conference : Matching genetics and environment : a new look at an old topic ; Barossa Valley, S.A. Australia 28th September - 1st October 2009
Start Page
84
End Page
87
Number of Pages
4
Start Date
2009-09-28
Finish Date
2009-10-01
ISSN
1328-3227
ISBN-13
9780646521039
Location
Barossa Valley, S. A.
Publisher
Association for the Advancement of Animal Breeding and Genetics
Place of Publication
Armidale
Peer Reviewed
Yes
Open Access
No
External Author Affiliations
Conference; Faculty of Arts, Business, Informatics and Education; TBA Research Institute; Universitetet for miljø- og biovitenskap; University of Edinburgh;
Era Eligible
Yes
Name of Conference
Association for the Advancement of Animal Breeding and Genetics. Conference