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Event-by-event motion compensation for small animal PET

conference contribution
posted on 06.12.2017, 00:00 authored by Weidong ZhouWeidong Zhou, A Kyme, S Meikle, R Fulton
In small animal PET imaging anaesthesia is usually required to eliminate motion. However, both anaesthesia and the alternative of forcibly restraining the animal, can disturb the very biochemical pathways that are of most interest in the brain. The ability to image the awake animal would represent a major advance. To this end we have investigated a motion correction technique suitable for small animal imaging on the microPET scanner, based on previous successful work in human brain PET. The efficacy of our technique was assessed on the microPET system by applying movements to a micro hot rod phantomduring list mode acquisition. Movements of the phantom in scanner coordinates were obtained using a commercially available optical motion tracking system operating in the visible spectrum. Motion correction, applied as corrective spatial transformations to individual lines of response, significantly reduced motion distortion. Our immediate goal is to perfect practical methods for marker attachment and motion tracking of small animals during microPET scans.

Funding

Other

History

Parent Title

2007 IEEE Nuclear Science Symposium Conference Record. Nuclear Science Symposium and Medical Imaging Conference, October 27-November 3, Honolulu, Hawaii.

Start Page

3109

End Page

3114

Number of Pages

6

Start Date

01/01/2007

ISSN

1082-3654

ISBN-10

1424409233

Location

Honolulu, Hawaii

Publisher

IEEE Operations Center

Place of Publication

Piscataway, NJ

Peer Reviewed

Yes

Open Access

No

Era Eligible

Yes

Name of Conference

Nuclear Science Symposium